Language of instruction: French / Français
Understand interactions between ionizing radiation and living cells
- Chapter I: Radiation-matter interaction o Stopping power, attenuation coefficient, fragmentation of heavy ions o From macroscopic dosimetry to microdosimetry o Radiochemistry - Chapter II: Fundamental radiobiology o DNA: Damage generation, chromosomal rearrangements and DNA repair o Cell death and survival (biological understanding and mathematical model) o Radiobiological quantities (LET, RBE, OER, ...) o Non-targeted effects - Chapter III: What about the clinic? o Introduction to radiotherapy o The 5 R's of radiobiology o Fractionation, a key element of radiobiology o Radiotherapy treatment sequence - Chapter IV: How to modify the cellular response to radiation? o By influencing the physical phase (dose deposition, dose rate, etc.) o By modifying the chemical phase o By modifying the biological phase (Repair, Repopulation, Redistribution, Radiosensitivity) - Chapter V: Space radiation biology o Introduction to space radiation sources o Space exploration and large LET particles o Radioprotection of astronauts
power point and notes taken by students
Oral exam