Industrial use of eukaryotic cells [SBIOM220]

Learning outcomes

At the end of the course, the student should be able to use the basic knowledge of cell and molecular biology acquired in previous years to critically analyse the use of eukaryotic cells in the biomedical industry, mainly in the mass production of recombinant (glyco)proteins in bioreactors and in toxicological/pharmacological tests on cell culture models.

Objectives

The objective of the course is to present a global vision of the use of eukaryotic cells in industry. Two axes will be mainly exploited: mass cell culture for the production of (glyco)proteins for use in the food industry and the production of (glyco)proteins for the food industry. The use of more or less differentiated cell models, used for toxicology and pharmacology, as alternatives to animal testing.

Content

The course will be composed of several seminars addressing a particular theme of the industrial use of eukaryotic cells. These seminars will be made as interactive as possible with the students and guests from the industrial and academic world. Depending on the programme, at least one visit to a biopharmaceutical company will also be scheduled. During these seminars, two main axes will be exploited: mass cell culture for the production of (glyco)proteins for therapeutic or vaccine use and the use of more or less differentiated cell models, used for toxicology and pharmacology, as alternatives to animal testing.