Hot Topics in Microbiomes, Diabetes and Cardiovascular Diseases [SBIOM128]
- 2 credits
- 22h
- 1st quarter
Language of instruction: EnglishTeacher: Arnould Thierry
Learning outcomes
To describe in details a major metabolic disease (Obesity and Insulin Resitance)
To understand the complexity of metabolic diseases, the fact that is mutltifactorial, the responses and contribution of various tissues/organs...as well as microflora
To cover major modern technologies ("omics") and their contribution in the understanding of the metabolic diseases.
Objectives
Analyse different aspects of an important metabolic question related to insulin resistance, obesity and associated diseases.
Describe and analyze the different roles palyed by many organs.
Characterize the different levels of analysis and different angles/aspects (epigentics, microbiome,...).
Review the techniques used in the studies devoted to study metabolism.
Content
Physiopathology of cardiac metabolism Metabolic Syndrome Cell Signalling and AMPK in the metabolism
Nutritional regulation of the gut microbiota: impact on gut peptides and inflammatory disorders in the context of obesity and type 2 diabetes
Gene expression and transcriptomics of pancreatic islets
Therapeutic approaches to treat obesity
Malnutrition and development
Sirtuins and metabolic adaptations
Teaching methods
Courses (2h) based on invited speakers and experts for various domains
Evaluations
Writing of a report that develops the input of "omics" in the understanding of metabolic diseases
Recommended readings
Recent reviews and research articles on different topics
Language of instruction
EnglishLocation for course
NAMUROrganizer
Faculté des sciencesRue de Bruxelles, 61
5000 NAMUR
