Pharmacognosy - Part I: Phytochemistry [MPHAB310]

Learning outcomes

At the end of this course, the student should know the main points of a monograph of the European Pharmacopoeia, know how to explain the interest of primary and secondary metabolites for the plant and man, know the generalities concerning all the classes of primary and secondary metabolites, know how to recognize and draw the basic structures of the various phytochemical classes seen in the course, To know how to comment on the structures and raw materials at the level of their biological properties, pharmacological activities, pharmaceutical uses, toxicity(ies) and undesirable effects as well as to be able to specify the principal origin of the studied compounds and conversely, to know the major constituents of a medicinal plant

Objectives

To train future pharmacists in the use of substances of plant or animal origin, whether they are used as such or as isolated molecules in therapeutics or as a source of inspiration in pharmacochemistry.

Content

Presentation of the different chemical classes of molecules involved in the activity of plants, responsible for their toxicity or of interest in pharmacotechnics or in food. The knowledge of the structures (based on their biosynthetic origin) is very important to evaluate their solubility, their stability and thus to better understand the extraction processes and the specific control methods (plants, extracts, essential oils...). In many cases, a relationship between these structures and pharmacological activity is established.