Elements of general pharmacology [MMEDB334]
- 4 credits
- 24h+8h
- 1st quarter
Learning outcomes
At the end of the course, the student will be able to explain the interaction of a drug with the human body and determine the pharmacokinetic properties of a drug.
Objectives
To integrate the concepts of biochemistry, physiology, signal transduction and ligand binding to receptors.
Content
• Course. 1. Introduction - Basic concepts 2. Pharmacokinetics 3. Pharmacodynamics 4. Special pharmacology • Tutorial. TD1 • Basics of pharmacokinetics • Passive diffusion (pH/pka) • Bolus IV in a single or bi-compartmental model TD2 Repeated Doses (RD) and Slow Infusion (specific to IR and HI) TD3 Converting in vitro clearance (CL) from a metabolism model to the individual's liver CL TD4 PK (PharmacoKinetic) and PD (PharmacoDynamic) studies in special populations. • Newborn • Child • Pregnant/lactating woman • Elderly person
Prerequisites
Physiologie générale [MMEDB222]Teaching methods
Mix of ex cathedra and inverted teaching combined with tutorials illustrating the pharmacokinetic concepts covered in class.
Evaluations
Written examination assessing theory and exercises based on open questions, True/False questions and exercises. The distribution of the mark is as follows: - The chapters Introduction, Pharmacodynamics and Special Pharmacology are graded /10 - The Pharmacokinetics chapter and the tutorials are graded /10.
Recommended readings
The PowerPoint slideshow, the practical booklet, and the research and review articles that support the study are available on Webcampus. General and Molecular Pharmacology (Edited byClementi & Fumagalli), WILEY Pharmacology (Edited by Hacker, Bachman, Messer), Elsevier-Academic Press Pharmacologie (Edited by Landry & Gies), Dunod
Language of instruction
French / FrançaisLocation for course
NAMUROrganizer
Faculté de médecinerue de Bruxelles
61
5000 NAMUR
P. 081724347
F. 081724327
administration-medecine@unamur.be
