Génie génétique et éléments de génomique [MBIOB215]

Learning outcomes

Notions of molecular genetics, for students at the second year of pharmacy, having acquired notions of organic Chemistry and Biology.

Objectives

Provide the basic principles of genetic engineering and genomics, to allow the future pharmacists to understand the new therapeutic approaches resulting from the control of molecular genetics and genomics.

Content

The course contents are divided in four main parts.

- DNA structure : DNA and chromatin, DNA in flux (recombinations, transpositions, ...) and horizontal gene transfer

- DNA functions : gene expression mechanisms

- Genetic engineering : basic principles in molecular biology, DNA sequencing, recombinant protein producrion and the genetic approaches (mutagenesis and transgenesis)

- Human genetic polymorphism and pharmacogenomics

Table of contents