Cell growth, differentiation and death [MBIMB302]
- 3 credits
- 30h
- 1st quarter
Language of instruction: French / FrançaisTeachers: Michiels Carine, Poumay Yves
Learning outcomes
To understand how an animal (mainly human) eukaryotic cell responds to stimuli from its environment, in terms of proliferation and growth, differentiation and programmed cell death. To understand the intervention of the deregulation of these mechanisms during the development of cancer cells.
Objectives
To achieve competence in understanding the mechanisms involved in initiating cell growth, differentiation and death; to know the main regulators involved in controlling these phenomena; to understand the regulatory mechanisms and their deregulation in pathological situations, particularly cancer.
Content
Cell growth and differentiation and their normal and pathological control. Signal transduction pathways from stimulus perception (receptor) to regulation of gene expression that are responsible for the adapted cellular response. Apoptosis and autophagy: mechanisms and regulations.
Prerequisites
Application pratique de la biologie des organismes [SBIOB154] et Biologie des organismes [SBIOB153] et Approche pratique de la biologie générale [SBIOB152] et Biologie générale [SBIOB151] et Cytologie [SVETB112]Teaching methods
Ex cathedra course in BAC3 Biomed based on power-point presentations available on webcampus and on reference books or articles. In 2022-2023, Professor Thierry ARNOULD will again act as substitute for Professor Carine MICHIELS. For students enrolled in the Master of Physics in the "Physics of living organisms" programme, the MBIMB302 course will be taught by self-study using the reference book "Cellular and Molecular Biology" (Karp, 4th edition).
Evaluations
Written exam: duration 2h30. This examination generally consists of open questions and MCQ questions relating to the parts taught by each teacher. A result of less than 7/20 in either part of the examination will cap the total result at 9/20. The exact modalities of the evaluation are subject to change when the examination timetable is drawn up, depending on the practical constraints that the faculty administration may face, or in the event of illness/force majeure/emergency with a placement, preventing the student from taking the examination on the date initially scheduled.
Recommended readings
For the part taught by Professor Poumay, the books "Molecular Biology of the Cell" (Alberts et al.) and "The Biology of Cancer" (Weinberg) are useful basic references (available at the BUMP). For the part taught by Professor Arnoud, the course materials and journal or research articles are references to be read.
Language of instruction
French / FrançaisLocation for course
NAMUROrganizer
Faculté de médecinerue de Bruxelles
61
5000 NAMUR
P. 081724347
F. 081724327
administration-medecine@unamur.be
